pentobarbital will minimize the extent or outcome of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Solid or moderate CYP3A4 inducers may possibly maximize amount of diazepam elimination; therefore, efficacy of diazepam could be lowered.
Following oral or parenteral administration, barbiturates easily cross the placental barrier and therefore are dispersed during fetal tissues with greatest concentrations present in the placenta, fetal liver, and Mind; fetal blood degrees approach maternal blood amounts next parenteral administration
pentobarbital will decrease the extent or outcome of disopyramide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.
pentobarbital will minimize the extent or result of midazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Warning when discontinuing CYP3A4 inducers which can be coadministered with hydrocodone; plasma concentrations of hydrocodone might raise and can lead to most likely fatal respiratory depression
pentobarbital will lower the extent or result of norgestrel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Moderate CYP3A4 inducers might lower progestin concentration; consider use of further barrier procedures
pentobarbital will reduce the level or effect of tinidazole by influencing hepatic/intestinal enzyme nembutal kaufen CYP3A4 metabolism. Use Warning/Watch.
Keep track of Closely (two)pentobarbital will minimize the level or impact of suvorexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Potent CYP3A4 inducers may perhaps minimize suvorexant efficacy; if greater suvorexant dose needed, do not exceed twenty mg/working day
pentobarbital will lower the level or impact of mestranol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will lessen the level or impact of fruquintinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. If coadministration with reasonable CYP3A4 inducers is unavoidable, carry on to administer fruquintinib at suggested dosage.
pentobarbital will lessen the extent or effect of alosetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Mysterious.
pentobarbital decreases amounts of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral method of each agents. Slight/Importance Mysterious.
pentobarbital will decrease the level or effect of trazodone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lessen the extent or result of estrogens conjugated synthetic by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.